Examining the Benefits and Drawbacks of Tamoxifen for Chemoprevention in High-Risk Women. Despite the fact that Tamoxife's benefits outweigh its downsides, a recent study found that not all women are suitable candidates for the drug's use. While baldness is not a side effect of tamoxifen, some people do experience hair thinning. Similar to hair thinning, a diminished libido is common postmenopausal and when oestrogen levels are low. Some women additionally attribute Tamoxifen's role in weight gain.
Women using Tamoxifen should steer clear of grapefruit and tangerines the most. Grapefruit is known to interact with a wide range of medications. Many resources on drug interactions specifically advise Tamoxife users to stay away from grapefruit. According to anecdotal evidence from multiple women, tamoxifen harms brain and central nervous system (CNS) cells.
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