What are the Applications of Next Generation Sequencing?

The 454, Illumina, Qiagen, and Ion Torrent (Thermo Fisher) platforms all use "sequencing by synthesis," which is arguably the most well-established sequencing technique. Each platform also uses its own set of proprietary technologies. A platform's instrument models may have different throughput and Next Generation Sequencing capacities.

For a specific instrument, sample loading chips and kits may also be scalable to offer additional higher-throughput options. When choosing, be sure to keep the application in mind. De novo sequencing and metagenomic sequencing may benefit from longer read lengths, while whole-genome or whole-transcriptome sequencing may call for higher throughputs.

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