Immunosuppressants suppress the immune system, increasing the risk of serious infections and other unwanted effects. Cyclophosphamide, for example, a powerful immunosuppressant, can induce bladder discomfort, bloody urine, and, in some cases, bladder cancer if used long-term. When cyclophosphamide is administered intravenously, the Vasculitis Treatment medicine mesna is also administered, which chemically counteracts some of cyclophosphamide's harmful effects on the bladder. For persons who use powerful immunosuppressants, a complete blood count is performed on a regular basis, often as frequently as once a week. Immunosuppressants may reduce the amount of blood cells.
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