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Epoprostenol is the first Pulmonary Arterial Hypertension Drugs that has been approved particularly to treat pulmonary hypertension. The best medication for treating advanced illness is flolan. According to studies, the Pulmonary Arterial Hypertension Drugs works effectively for treating pulmonary arterial hypertension (PAH), as well as pulmonary hypertension caused by scleroderma, lupus, congenital heart disease, diet pills, and stimulants (PH). The patient must make a significant commitment to Flolan. Through the use of a unique intravenous catheter, this drug is continuously infused into the patient. Daily mixing and refrigeration of the drug are required. To avoid dangerous infections, catheter care must be taken very seriously. Headache, jaw discomfort, flushing, rashes, and upset stomach are typical adverse effects.