Given their abilityto selectively direct a cell mediated immune response against cancer cells and,thereby, offer prolonged periods of disease remission, several CAR-T celltherapies are expected to achieve blockbuster status
Roots Analysis is pleased toannounce the publication of its recent study, titled, “CAR-T Cell Therapies Market (3rdEdition) by Target Indications (NHL, Multiple Myeloma, Chronic LymphocyticLeukemia, Acute Lymphoblastic Leukemia, Follicular Lymphoma, Mantle CellLymphoma, Hepatocellular Carcinoma and Others), Target Antigens (CD19, BCMA,CD19 / CD22, GPC3 and EGFR), Key Players and Key Geographies (North America,Europe, Asia Pacific, Latin America, Middle East and North Africa, and Rest of theWorld) – Industry Trends and Global Forecasts, 2021-2030”
The features an extensive study of the currentmarket landscape and the future potential of CAR-T cell therapies. The reporthighlights the efforts of both industry players and academic organizations inthis rapidly evolving segment of the biopharmaceutical industry. Amongst otherelements, the report features the following:
§ A detailed assessmentof the current market landscape of drug developers engaged in the developmentof CAR-T cell therapies.
§ Detailed profiles ofmarketed and mid-to late stage clinical products (shortlisted on the basisof the stage of development).
§ An analysis of theCAR constructs of clinical-stage CAR-T therapies based on the generation ofCAR-T therapy.
§ An analysishighlighting the key opinion leaders (KOLs) in this domain. It features a 2×2matrix assessing the relative experience of KOLs shortlisted based on theircontributions (in terms of involvement in various clinical studies) tothis field.
§ An analysis of thevarious CAR-T cell therapy focused clinical trials registered across the world,between 2009 and 2019.
§ An overview of thevarious focus therapeutic areas of therapy developers, including an assessmentof the opportunity (in terms of revenue generation potential from therapysales) across oncological and non-oncological disease indications.
§ A detailed discussionon innovative technology platforms that are being used for the development of CAR-Tcell therapies.
§ An analysis of the partnerships that have been establishedin the recent past.
§ An analysis of the investments that have been made intocompanies that have proprietary CAR-T cell based products / technologies.
§ A case study on other T-cell based therapies, apart fromCAR-Ts, including a detailed analysis of approved / pipeline products.
§ A case study on manufacturing cell therapy products,highlighting the key challenges, and a detailed list of contract serviceproviders and in-house manufacturers involved in this space.
§ An elaborate discussion on various factors that form thebasis for the pricing of cell-based therapies.
§ An analysis of the prevalent and emerging trends in thisdomain, as represented on the social media platform, Twitter.
§ A review of the key promotional strategies that have beenadopted by the developers of the marketed CAR-Tcell therapies.
§ A detailed marketforecast, featuring analysis of the current and projected future opportunityacross key market segments (listed below)
- Type of target disease Indication
- Non-Hodgkin’s lymphoma
- Multiple myeloma
- Chronic lymphocytic leukemia
§ Acutelymphoblastic leukemia
§ Mantle cell lymphoma
- Hepatocellular carcinoma
§ Colorectal cancer
§ Typeof Target Antigens
- CD19, CD22
§ KeyGeographical Regions
- North America
- Asia Pacific
- Latin America
- Middle East and North Africa
- Rest of the World
§ Transcripts ofinterviews held with the following senior level representatives of stakeholdercompanies
- Tim Oldham (Chief Executive Officer, Cell Therapies)
- Troels Jordansen (Chief Executive Officer, Glycostem Therapeutics)
- Wei (William) Cao (Co-Founder, Chairman and Chief Executive Officer, Gracell Biotechnologies)
- Miguel Forte (Chief Operating Officer, TxCell)
- Adrian Bot (Vice President, Scientific Affairs, Kite Pharma)
- Vincent Brichard (Vice President, Immuno-Oncology, Celyad)
- Brian Dattilo (Manager of Business Development, Waisman Biomanufacturing)
- Aino Kalervo (Competitive Intelligence Manager, Strategy & Business Development, Theravectys)
- Xian-Bao Zhan (Professor of Medicine and Director, Department of Oncology, Changhai Hospital)
- Enkhtsetseg Purev (Assistant Professor of Medicine, University of Colorado)
Key companies coveredin the report
- bluebird bio
- CARsgen Therapeutics
§ Celgene (A BristolMyers Squibb Company)
- Cellular Biomedicine Group
- Innovative Cellular Therapeutics
- Iovance Biotherapeutics
- Kite Pharma (A Gilead Sciences Company)
- Kuur Therapeutics
- Lion TCR
- Noile-Immune Biotech
- Shanghai GeneChem
- Sinobioway Cell Therapy
- Takara Bio
- Ziopharm Oncology
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