When given to people in an acute dose, aspartame is not hazardous. Aspartame was given to humans in single bolus doses of up to 200 mg kg1 body weight. Aspartic acid, phenylalanine, and methanol concentrations in the blood were substantially below any potentially dangerous levels. Methanol's harmful effects in humans are caused by the accumulation of its metabolite, formate. After this excessive bolus dosage of aspartame, blood formate concentrations did not rise.
One of the primary benefits of Aspartame is that it is a low-calorie sweetener. This means that it can be used to reduce the calorie content of food and drink products without sacrificing taste. This can be especially beneficial for people who are trying to manage their weight or reduce their caloric intake. Another benefit of aspartame is that it does not promote tooth decay like sugar does. This is because aspartame is not metabolized by the bacteria in the mouth that cause cavities. This makes it an attractive alternative to sugar for people who are concerned about their dental health.
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