Over time,significant strides have been made in immune checkpoint research, resulting inthe discovery of several inhibitory (LAG-3, TIM-3, TIGIT, VISTA and B7-H3) andstimulatory receptors (OX40, ICOS, GITR, 4-1BB and CD40), which are beinginvestigated as potential targets for therapy development. Further, studies ofcombinatorial immune checkpoint blockade / co-stimulation, targeting newlyidentified checkpoints along with known checkpoint inhibitor therapies, havedemonstrated promising clinical outcomes as well.
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The USD 12 billion(by 2030) financial opportunity within the next generation immune checkpointmodulators market has been analyzed across the following segments:
§ Target Disease Indication
- Breast Cancer
- Chronic Lymphocytic Leukemia
- Colorectal Cancer
- Head and Neck Cancer
- Lung Cancer
- Lupus Nephritis
- Melanoma
- Multiple Myeloma
- Primary Sjögren's Syndrome
- Others
§ Target Immune Checkpoint
- B7-H3
- CD38
- CD40
- CD47
- Others
§ Mechanism of Action
- Inhibitory
- Stimulatory
§ Therapeutic Modality
- Monoclonal Antibody
- Small Molecule
§ Type of Therapy
- Monotherapy
- Combination Therapy
§ Route of Administration
- Intravenous
- Subcutaneous
- Others
§ Key Geographical Regions
- North America
- Europe
- Asia-Pacific and the Rest of the World
The NextGeneration Immune Checkpoint Inhibitors and Stimulators Market, 2020-2030. report features thefollowing companies, which we identified to be key players in this domain:
§ Bristol Myers Squibb
§ GlaxoSmithKline
§ Incyte
§ Novartis
§ Trillium Therapeutics
Table of Contents
1. Preface
2. Executive Summary
3. Introduction
4. Current Market Landscape: Clinical and PreclinicalMolecules
5. Market Landscape: Therapies Targeting Cd47
6. Market Landscape: Therapies Targeting 4-1bb
7. Clinical Trial Analysis
8. Company Profiles: Next Generation Inhibitors andStimulators
9. Academic Grants Analysis
10. Partnerships and Collaborations
11. Target Competitiveness Analysis
12. Big Pharma Initiatives
13. Market Forecast and Opportunity Analysis
14. Concluding Remarks
15. Executive Insights
16. Appendix 1: Tabulated Data
17. Appendix 2: List of Companies and Organizations
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Contact Details
Gaurav Chaudhary
+1 (415) 800 3415
gaurav.chaudhary@rootsanalysis.com
