When the bloodstream and tissues accumulate unusually high quantities of uric acid (also known as hyperuricemia), Gouty Arthritis develops. A basic waste product called uric acid is typically eliminated by the kidneys through the urine. However, when the kidneys struggle to eliminate uric acid, it builds up to excessive levels in the body. Hyperuricemia is the name of the condition, which can cause gout. While others with the same high levels of uric acid tend to get gout, some people, despite having high levels, don't. There is no explanation for why this incident occurs. The synovium or joint lining becomes inflamed as a result of uric crystals building up in the joints.
Due to the big toe having the lowest temperature, these uric crystals also have a propensity to collect there. After a number of years, uric acid crystals that have accumulated in the joints produce enormous deposits called tophi that resemble lumps just beneath the skin. Tophi can develop around the affected fingertip, toe, or even the outside part of the ear. If the tophi are not prevented or treated in a timely manner, they can spread and put pressure on your bone and cartilage, perhaps resulting in damaged joints. Chronic tophaceous gout is the term used to describe the ailment when this occurs.
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