The main factors that hinder the growth of the global antiplatelet drugs market include limitations in effectiveness, safety, and tolerability of some antiplatelet drugs. For example, in July 2018, according to the National Center for Biotechnology Information, anti-platelet drugs can irritate the lining of the stomach which leads to gastrointestinal side effects such as indigestion and stomach pains. Moreover, patients using these drugs may be more prone to nosebleeds, bruising or bleeding for longer than usual since they reduce the ability of the blood to clot. According to the Journal of Clinical Gastroenterology 2018 report, most spontaneous bleeding in patients treated with anti-platelet drugs occurs in the gastrointestinal tract, with an incidence of 2-3% with dual antiplatelet therapy.
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