Explain Natural Killer Cells

On the peripheral blood smear, natural killer cells are visible as a distinctive group of circulating lymphocytes. They appear as large granular lymphocytes on Wright-Giemsa staining. They have prominent nuclei, large nuclei, and coarse chromatin. They have an abundance of azurophilic granules in their basophilic cytoplasm, which do not react with peroxidase.

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