The small intestine is generally where iron is absorbed, however the stomach is crucial in increasing the iron's biological availability. Moreover, the small intestine is where calcium is usually absorbed. These minerals can also be absorbed from the colon if the body's needs cannot be met by its absorption pathway. Polydextrose has been shown to ferment slowly and gradually, and its positive effects are either mediated by the metabolites it produces or by changes in the microbiota. The colon's luminal pH will decrease as a result of the generation of SCFA, which will also make calcium more soluble. With the SCFA, some chelation of iron may occur, which would also make passive absorption easier.
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