Every year, between 100,000 and 300,000 deaths in the U.S. are attributed to Venous Thromboembolism (International Society on Thrombosis and Hemostasis, Inc.). In Europe, there are 544,000 deaths a year, which is a far larger amount. Up to 60% of VTE occurrences, according to estimates, are thought to happen during or immediately after hospitalisation. This avoidable illness is frequently disregarded as a serious public health issue that causes fatalities. The pharmacological approaches primarily target the non-specific pathways in the coagulation cascade using either new generation anticoagulants or conventional anticoagulants. One of the main risk factors for pharmaceutical therapies is excessive bleeding.
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