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Compounds Made Up Of Iron And Oxygen Are Known As Iron Oxide
Iron Oxide

Given intravenously, ultrasmall superparamagnetic Iron Oxide particles (USPIOs) with a median diameter no less than 50 nm have been explored as blood-pool agents to improve liver imaging in cirrhotic patients and to visualise lymph nodes. They are made up of non-stoichiometric microcrystalline iron oxide cores that are covered with siloxanes or dextrans (in ferrumoxides) (in ferumoxsils). The most widely used type of iron oxide is magnetite, which is a combination of Fe2O3 and FeO; Fe2O3 and Fe3O4 can also be employed.

The reticuloendothelial system stores the particles after injection. There is a difference between a liver tumour and a normal liver because liver tumours have few or no reticuloendothelial cells. These contrast compounds have few side effects and are well tolerated. Low back discomfort, nausea and diarrhoea, urticaria, flushing, disorientation, and muscular spasms are some of the side effects that have been recorded. With these particulate Iron Oxide treatments, adverse responses are more common than with gadolinium chelates. However, given that all of the reactions are self-limiting and only a small number are severe, there is not much cause for alarm.

 

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