The Glucosamine sulphate salt is one half of the disaccharide subunit of keratan sulphate, which reduces in osteoarthritic patients. Hyaluronic acid (found in articular cartilage and synovial fluid) is made up of glucuronic acid and N-acetylglucosamine repeating dimeric units. Direct stimulation of chondrocytes, incorporation of sulphur into cartilage, and protection against degradative processes within the body via changed gene expression are all possible modes of action for glucosamine's chondroprotective function. The precise mechanism of action for glucosamine's potential effect is uncertain.
Glucosamine is a naturally occurring compound found in the body that plays an important role in the formation and repair of cartilage. It is commonly used as a dietary supplement to relieve joint pain and inflammation associated with osteoarthritis. Glucosamine is produced naturally in the body from glucose and amino acids. It is an important building block of cartilage, which is the connective tissue that cushions the joints. Glucosamine helps to maintain the integrity and function of cartilage by stimulating the production of proteoglycans, which are the major components of cartilage. Proteoglycans help to attract and retain water in the cartilage, which provides it with its cushioning properties.
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