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Tramadol is a highly effective formulation containing acetaminophen. As a result, doctors never recommend this medication to treat pain in children under the age of 12. Tramadol (Ultram) is a powerful pain reliever from the tramadol family. Buy Tramadol Online is available in extended-release and immediate-release formulations on the market, and you can take the preferred formulation according to your doctor's instructions. This medication begins to work within 30 to 60 minutes and stays in your system for up to 4 to 6 hours. It is a synthetic opioid that works on the nerve cells and spine in the central nervous system to reduce pain.