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How IVF-PGD Can Help Prevent Genetic Disorders in Your Child

MedPort on Health Fitness - Having a healthy child is every parent’s dream. People having a history of a genetic disorder or any kind of inheritable disease in their family have a higher chance of having that condition passed on to their child. They may be even afraid to get married or have children.

Once a patient from an African country who had a condition called sickle cell anemia contacted us regarding his concern about getting married to a woman having the same condition. He wanted to know if there is any method by which he can make sure that their child will not get their disease inherited. Just like him, there are many parents out there having similar concerns about having a healthy child. This article on IVF-PGD will be helpful for them to know their possibilities for preventing such known diseases or abnormal conditions being passed on to their child.

In-Vitro Fertilization or IVF is an Assisted Reproductive Technology that involves collecting the male and female reproductive cells, combining them in a laboratory and then transferring the embryo into the uterus of the mother. IVF treatments have fulfilled the parenthood dreams of millions of couples across the globe. For more details about IVF, you may read our article “IVF Treatment in India – Cost, Process, Best Doctors and Hospitals“

Using IVF, it is possible to conduct a genetic screening or diagnosis of the embryos before transferring them into the uterus. This is known as Pre-implantation Genetic Diagnosis (PGD). This technique is widely used nowadays to choose the best quality embryos for transferring into the mother’s womb.

PGD stands for Pre-implantation Genetic Diagnosis. It is a diagnosis process usually conducted as part of artificial reproduction techniques. This is performed to analyze the genetic characteristics of an embryo.

The genes of the parents are passed on to their children in different patterns. A certain combination of genes can cause a harmful disease phenotype. PGD helps to check for the presence of any known abnormal gene in the genotype of an embryo. If the parents’ pedigree has the presence of an abnormal gene that may cause threatening genetic disorders, there is a high chance for this to be passed on to their child.

During artificial reproduction techniques like in-vitro fertilization (IVF), the embryos are transferred to the mother’s womb after a certain stage of development. Before placing the embryo into the uterus, PGD can be employed to choose the embryos which don’t have a particular abnormal gene or a combination of genes inherited in their genotype. This avoids the need for abortion on detecting a genetic abnormality after proceeding with the pregnancy. PGD is highly significant for parents with a clinical history of any genetic disease in their family, to conceive a healthy baby.

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