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The concept of targeted protein degradation presentsrevolutionary drug development opportunities and is anticipated to bring abouta paradigm shift in modern healthcare. The first targetedprotein degrader, called proteolysis targeting chimera (PROTAC), was developedabout a decade ago. Presently, a variety of other such chemical entities andmolecular glues are under investigation. In fact, certain pipeline candidates arealready in the mid to late-phase trials and are anticipated to soon enter themarket.
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The USD 3.6 billion (by 2030) financial opportunitywithin the target protein degradation market has been analyzed across thefollowing segments:
§ Typeof payment of licensing agreements
§ Upfrontpayments
§ Milestonepayments
§ Type of protein degrader
§ Degronimids
§ PROTACs
§ SARDs/ SERDs
§ SpecificBET and DUB inhibitors
§ Otherprotein degraders
§ Therapeutic area
§ Neurodegenerativedisorders
§ Oncologicaldisorders
§ Othertherapeutic areas
§ Routeof administration
§ Oral
§ Intravenous
§ Otherroutes
§ Keygeographical region
§ NorthAmerica
§ Europe
§ Asia-Pacific
The Targeted Protein Degradation Market: Focus on Therapeuticsand Technology Platforms (based on Degronimids, ENDTACs, EpichaperomeInhibitors, Hydrophobic Tags, IMiDs, LYTACs, Molecular Glues, PHOTACs, PROTACs,Protein Homeostatic Modulators, SARDs, SERDs, SNIPERs, and Specific BET and DUBInhibitors), 2020-2030 report features thefollowing companies, which we identified to be key players in this domain:
§ Arvinas
§ CaptorTherapeutics
§ Celgene
§ Genetech
§ KymeraTherapeutics
§ MissionTherapeutics
§ Progenra
§ RadiusHealth
§ SanofiGenzyme
§ Zenopharm
Table of Contents
1. Preface
2. Executive Summary
3. Introduction
4. Current Market Landscape
5. Company Profiles
6. Clinical Trial Analysis
7. KOL Analysis
8. Publication Analysis
9. Funding and Investment Analysis
10. Partnerships and Collaborations
11. MarketSizing and Opportunity Analysis
12. Executive Insights
13. Concluding Remarks
14. Appendix 1: Tabulated Data
15. Appendix 2: List of Companies andOrganizations
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